Donald P. Briskin

Professor Emeritus

Education

  • B.S., 1977, University of Southern California, Los Angeles
  • Ph.D., 1981, University of California at Riverside

Academic Positions

  • Post-Doctoral Fellow, Department of Biology, McGill University, Montreal, Quebec, Canada (1982 - 1983)
  • Plant Physiologist, USDA-ARS Crops Research Laboratory and Assistant Professor of Biochemistry, Department of Chemistry and Biochemistry, Utah State University, Logan, UT (1983 - 1985)
  • Assistant Professor of Plant Biochemistry/Physiology, Department of Agronomy, University of Illinois at Urbana-Champaign (1985 - 1988)
  • Associate Professor of Plant Biochemistry/Physiology, Department of Agronomy, University of Illinois at Urbana-Champaign (1988 - 1992)
  • Professor of Plant Biochemistry/Physiology, Department of Agronomy, University of Illinois at Urbana-Champaign (1992 - 1998)
  • Professor of Plant Biochemistry/Physiology (joint appointment), Department of Plant Biology, University of Illinois at Urbana-Champaign (1998 - present)
  • Associate Department Head, Department of Natural Resources and Environmental Sciences, University of Illinois at Urbana-Champaign (2000 - 2003)
  • Professor of Plant Biochemistry/Physiology, Department of Natural Resources and Environmental Sciences, University of Illinois at Urbana-Champaign (1999 - present)

Research Interests

  • Medicinal plants and phytomedicines, GMO materials in food products.

    We are examining how the growth environment and postharvest processing of medicinal plants affects the recovery of phytomedicinal chemicals and the quality of herbal medicines. In addition we are developing in vitro tissue culture systems for growth of medicinal plants and production of phytomedicinal chemicals. An additional area of research is focused on examining GMO (genetically-modified organisms) materials in food products, especially the development of assays for detection of GMO products.

Honors, Recognition, and Outstanding Achievements

  • Paul A. Funk Recognition Award, Univ. of IL College of ACES - 2005

Honors, Recognition, and Outstanding Achievements for Research

  • Arnold O. Beckman Research Award, University of Illinois - 1985
  • McKnight Individual Research Award in Plant Biology, McKnight Foundation - 1986
  • Designated as "Beckman Fellow" in the Univ. of IL Center for Advanced Study - 1987
  • Designated as "University Scholar", Univ. of IL - 1988
  • Young Crop Scientist Award, Crop Science Society of America - 1988
  • Arnold O. Beckman Research Award, University of Illinois - 1990
  • Alumni Award of Merit, Gamma Sigma Delta and Univ. of Cal, Riverside - 1990
  • Certificate of Merit for Service on the Editorial Board of PLANT PHYSIOLOGY - 1992
  • Faculty Award for Excellence in Research, Univ. of IL College of Agriculture - 1993

Honors, Recognition, and Outstanding Achievements for Teaching

  • Present on the List of University of Illinois Instructors Rated Excellent by their Students - 1986, 1988, 1989, 1990, 1991, 1992, 1993, 1994, 1995, 1996, 1997, 1998, 1999. 2000, 2001, 2002, 2003, 2204, 2005
  • Listed as “Excellent Teacher” in the “Daily Illini Student Orientation Guide” - 1999
  • Appointed to Univ. of IL College of Liberal Arts and Sciences Teaching Academy - 1999
  • Senior Faculty Award for Excellence in Teaching, Univ. of IL, College of ACES - 2001
  • John Clyde and Henrietta Spitler Award for Teaching, Univ. of IL College of ACES - 2002
  • UIUC Campus Award for Excellence in Off-Campus Teaching - 2004

Selected Articles in Journals

  • Briskin DP, RT Leonard 1979. Ion transport in isolated protoplasts from tobacco suspension cells. III. Membrane potential. Plant Physiol 64: 959-962
  • Briskin DP, RT Leonard 1980. Isolation of tonoplast vesicles from tobacco protoplasts. Plant Physiol 66: 684-687
  • Briskin DP, RT Leonard 1982. Phosphorylation of the adenosine triphosphatase in a deoxycholate-treated plasma membrane fraction from corn roots. Plant Physiol 70: 1459-1464
  • Briskin DP, RT Leonard 1982. Partial characterization of a phosphorylated intermediate associated with plasma membrane ATPase of corn roots. Proc Natl Acad Sci, USA 79: 6922-6926
  • Briskin DP, RJ Poole 1983. Characterization of a K+-stimulated adenosine triphosphatase associated with the plasma membrane of red beet. Plant Physiol 71: 350-355
  • Briskin DP, RJ Poole 1983. Plasma membrane ATPase of red beet forms a phosphorylated intermediate. Plant Physiol 71: 507-512
  • Briskin DP, RJ Poole 1983. Role of magnesium in the plasma membrane ATPase of red beet. Plant Physiol 71: 969-971
  • Briskin DP, RJ Poole 1983. Evidence for a b-aspartyl phosphate residue in the phosphorylated intermediate of the red beet plasma membrane ATPase. Plant Physiol 72: 1133-1135
  • Briskin DP, RJ Poole 1983. The plasma membrane ATPase of higher plant cells. What's New in Plant Physiology, Vol. 14, No. 1
  • Poole RJ, DP Briskin, Z Kratky, RM Johnstone 1984. Density gradient localization of plasma membrane and tonoplast from storage tissue of red beet. Characterization of proton transport and ATPase acitivity in tonoplast vesicles. Plant Physiol 74: 549-556
  • Briskin DP. 1984. A current perspective on the plasma membrane ATPase of higher plant cells. In: WJ Cram, R Rybova, K Janacek, K Sigler, eds, MEMBRANE TRANSPORT IN PLANTS, Academia, Prague, pp. 531-537
  • Briskin DP, RJ Poole 1984. A catalytic aspartyl phosphate residue in the plasma membrane ATPase of red beet. In: WJ Cram, R Rybova, K Janacek, K Sigler, eds, MEMBRANE TRANSPORT IN PLANTS, Academia, Prague, pp. 542-5433
  • Briskin DP, RJ Poole 1984. Characterization of the solubilized plasma membrane ATPase of red beet. Plant Physiol 76: 26-30
  • Briskin DP, WR Thornley, RJ Poole 1984. Vanadate-dependent NADH oxidation in microsomal membanes of sugarbeet. Arch Biochem Biophys 236: 228-237
  • Briskin DP, RJ Poole 1985. Proton pump and ATPase activities in tonoplast vesicles from the storage tissue of red beet. In: B Marin, ed, BIOCHEMISTRY AND FUNCTION OF VACUOLAR ATPase IN FUNGI AND PLANTS, Springer-Verlag, Berlin, pp. 163-174
  • Walderhaug MO, RL Post, G Saccomani, RT Leonard, DP Briskin 1985. Structural relatedness of four membrane bound adenosine triphosphatases around their active sites of phosphorylation. J Biol Chem 260: 3852-3859
  • Briskin DP, WR Thornley, JL Roti-Roti 1985. Target molecular size of the red beet plasma membrane ATPase. Plant Physiol 78: 642-644
  • Briskin DP, WR Thornley, RE Wyse 1985. Membrane transport in isolated vesicles from sugarbeet taproot. I. Isolation and characterization of energy-dependent, H+- transporting vesicles. Plant Physiol 78: 865-870
  • Briskin DP, WR Thornley, RE Wyse 1985. Membrane transport in isolated vesicles from sugarbeet taproot. II. Evidence for a sucrose/H+-antiport. Plant Physiol 78: 871-875
  • Briskin DP, WR Thornley 1985. Plasma membrane ATPase of sugarbeet. Phytochemistry 24: 2797-2802
  • Wyse RE, B Aloni, DP Briskin 1985. Sucrose transport: regulation and mechanism at the tonoplast. In: R Heath, J Preiss, eds, REGULATION OF CARBON PARTITIONING IN PHOTOSYNTHETIC TISSUE, Plant Physiology Press, pp. 231-253
  • Briskin DP 1986. Sucrose transport in isolated tonoplast vesicles from sugarbeet taproot. In: J Chronshaw, R Giaquinta, W Lucas, eds, PHLOEM TRANSPORT, Alan R. Liss Inc, pp. 111-123
  • Briskin DP 1986. Intermediate reaction states for the red beet plasma membrane ATPase. Arch Biochem Biophys 248: 106-115
  • Lew RR, DP Briskin, RE Wyse 1986. Ca2+ uptake by endoplasmic reticulum from zucchini shoots. The use of chlorotetracycline as a probe for Ca2+ uptake. Plant Physiol 82: 47-53
  • Briskin DP 1986. Plasma membrane H+-transporting ATPase: Role in potassium ion transport?. Physiol Plant 68: 159-163
  • Briskin DP, RT Leonard, TK Hodges 1987. Isolation of the plasma membrane: General principles and membrane markers. Methods Enzymol 148: 542-558
  • Griffiths HM, CS Tepper, DP Briskin, AJ Anderson 1987. The effect of extracellular products from Colletotrichum lindemuthinium on tonoplast function. Phytochemistry 26: 21-24
  • Giannini JL, GM Miller, JL Pushnik, DP Briskin 1987. Fluoride effects on plasma membrane ATPase in sugarbeet storage tissue. Plant Science 53: 39-44
  • Giannini JL, GM Miller, DP Briskin 1987. Membrane transport in isolated vesicles from sugarbeet taproot. III. Effects of fluoride on ATPase activity and transport. Plant Physiol 83: 709-712
  • Singh SP, BVS Kesav, DP Briskin 1987. Reconstitution and rapid purification of the red beet plasma membrane ATPase. Physiol Plant 69: 617-626
  • Giannini JL, LH Gildensoph, DP Briskin 1987. Selective production of sealed plasma membrane vesicles from red beet (Beta vulgaris L.) storage tissue. Arch Biochem Biophys 254: 621-630
  • Coulombe RA, DP Briskin, RJ Keller, WR Thornley, RP Sharma 1987. Vanadatedependent oxidation of pyridine nucleotides in rat liver microsomal membranes. Arch Biochem Biophys 255: 267-273
  • Giannini JL, DP Briskin 1987. Proton transport in plasma membrane and tonoplast vesicles from red beet (Beta vulgaris L.) storage tissue. A comparative study of anion effects on ΔpH and ΔΨ. Plant Physiol 84: 613-618
  • Giannini JL, LH Gildensoph, I Niesman, DP Briskin 1987. Calcium transport in sealed vesicles from Red Beet (Beta vulgaris L.) storage tissue. I. Characterization of Ca2+- pumping ATPase associated with the endoplasmic reticulum of red beet (Beta vulgaris L.) storage tissue. Plant Physiol 85: 1129-1136
  • Giannini JL, JL Ruiz-Cristin, DP Briskin 1987. Calcium transport in sealed vesicles from Red Beet (Beta vulgaris L.) storage tissue. II. Characterization of 45Ca2+ uptake into plasma membrane vesicles. Plant Physiol 85: 1137-1142
  • Giannini JL, DP Briskin 1988. Pyridine nucleotide oxidation by plasma membrane vesicles from Red Beet (Beta vulgaris L.) storage tissue. Arch Biochem Biophys 260: 653-660
  • Giannini JL, DP Briskin, JS Holt, JD Paxton 1988. Inhibition of plasma membrane and tonoplast H+-transporting ATPases by glyceollin. Phytopathol 78: 1000-1003
  • Briskin DP 1988. Chemical equivalence of phosphoenzyme reaction states in the catalytic mechanism of the red beet (Beta vulgaris L.) plasma membrane ATPase. Plant Physiol 88: 77-83
  • Giannini JL, J Holt, DP Briskin 1988. Isolation of sealed plasma membrane vesicles from Phytophthora megasperma f. sp. glycinia. I. Characterization of proton pumping and ATPase activity. Arch Biochem Biophys 265: 337-345
  • Giannini JL, JS Holt, DP Briskin 1988. Isolation of plasma membrane vesicles from Phytophora megasperma f. sp. glycinea. II. Characterization of Ca2+ transport and glyceollin effects. Arch Biochem Biophys 266:644-649
  • Briskin DP 1988. Phosphorylation and dephosphorylation reactions of the red beet (Beta vulgaris L.) plasma membrane ATPase observed in the transient state. Plant Physiol 88: 84-91
  • Giannini JL, JL Ruiz-Cristin, DP Briskin 1988. A small scale procedure for the isolation of transport competent vesicles from plant tissues. Anal Biochem 174: 561-567
  • Takemoto JY, JL Giannini, DP Briskin 1989. Syringomycin effects on plasma membrane Ca2+ transport. In: E. Granita, R. Durbin, A. Ballio eds, Phytoxins and Plant Pathogens, Springer Verlag, Berlin, pp. 167-175
  • Schrader LE, DP Briskin 1989. Mineral nutrition of soybeans. In Proceedings of the World Conference on Soybeans,Buenos Aires, Argentina
  • Coulombe RA, DW Reif, RJ Keller, DP Briskin, SD Aust, WR Thornley, RP Sharma 1989 Vanadate stimulation of pyridine nucleotide oxidation in mammalian liver microsoma membranes. In: MG Simic, KA Taylor, JF Ward, eds, Oxygen Radicals in Biology and Medicine, Plenum Pub. Co., New York. pp. 777-780
  • Giannini JL, DP Briskin 1989. The effect of assay composition, detergent solubilization, and reconstitution on red beet (Beta vulgaris L.) plasma membrane H+-ATPase kinetic properties. Plant Sci 60: 189-193
  • Briskin DP, I Reynolds-Niesman 1989. Changes in the target molecular size of the red beet plasma membrane ATPase during solubilization and reconstitution. Plant Physiol 90: 394-397
  • Gildensoph LH, DP Briskin 1989. Modification of an essential arginine residue associated with the plasma membrane ATPase of red beet (Beta vulgaris L.) storage tissue. Arch Biochem Biophys 271: 254-259
  • Ruiz-Cristin J, AJ Chodera, DP Briskin 1989. A modified method for the productions of 36ClO3- for use in plant nitrate transport studies. Anal Biochem 182: 146-150
  • Williams LE, DP Briskin 1989 Sucrose uptake into tonoplast vesicles of red beet. In: J Dianty, MI DiMichelis, E Marre, F Rasi-Caldogno, eds, Plant Membrane Transport: The Current Position. Elsevier Science Publishers, Amsterdam pp. 195-196
  • Briskin DP 1990. Transport in plasma membrane vesicles-approaches and perspectives. In: I. Møller, K. Larsson, eds. The Plant Plasma Membrane-Structure, Function and Molecular Biology. Springer-Verlag Pub., Heidelberg pp. 154-181
  • Williams LE, SE Schuler, DP Briskin 1990. Further characterization of the red beet plasma membrane Ca2+-ATPase using GTP as an alternative substrate. Plant Physiol 92: 747-754
  • Briskin DP 1990 Importance of developing an understanding of membrane transport processes at the biochemical level. In: R.D. Munson, ed. The Physiology, Biochemistry, Nutrition and Bioengineering of Soybeans: Implications for Future Management. Potash and Phosphate Institute pp. 86-89
  • Chodera AJ, DP Briskin 1990. Chlorate transport in isolated tonoplast vesicles from red beet (Beta vulgaris L.) storage tissue. Plant Sci 67: 151-160
  • Giannini JL, JS Holt, DP Briskin 1990. The effect of glyceollin on Phytophthora megasperma f. sp. glycinea plasma membrane proton transport using sealed vesicles. Plant Sci 68: 39-45
  • Briskin DP, LH Gildensoph, S Basu 1990. Characterization of the Ca2+-ATPase of the plant plasma membrane using isolated membrane vesicles. In: RT Leonard, PK Hepler, eds. Calcium in Plant Growth and Development. American Society of Plant Physiologists pp. 46-54
  • Suhayda CG, JL Giannini, DP Briskin, MC Shannon 1990. Electrostatic changes in Lycopersicon esculentum root plasma membrane resulting from salt stress. Plant Physiol 93: 471-478
  • Gildensoph LH, DP Briskin 1990. Modification of the red beet plasma membrane H+- ATPase by the histidine-specific reagent diethylpyrocarbonate. Plant Physiol 94: 696-703
  • Briskin DP 1990. The plasma membrane H+-ATPase of higher plant cells: Biochemistry and transport function. Biochem Biophys Acta 1019: 95-109
  • Briskin DP 1990. The Ca2+-ATPase of the plant plasma membrane. Plant Physiol 94: 397-400
  • Briskin DP, I Reynolds-Niesman 1991. Determination of H+/ATP stoichiometry for the plasma membrane H+-ATPase from red beet (Beta vulgaris L.) storage tissue. Plant Physiol 95: 242-250
  • Ruiz-Cristin JL, DP Briskin 1991. Characterization of a H+/NO3- symport associated with plasma membrane vesicles of maize roots using 36ClO3- as a radiotracer analog. Arch Biochem Biophys 285: 74-82
  • Giannini JG, JS Holt, DP Briskin 1991. The effect of glyceollin on soybean (Glycine max L.) tonoplast and plasma membrane vesicles. Plant Sci 74: 203-211
  • Briskin DP, JB Hanson. 1992. How does the plasma membrane H+-ATPase pump protons? J Exp Bot 43: 269-289
  • Ho I, DP Briskin 1992. Chemical modification of the red beet plasma membrane H+- ATPase with N-acetylimidazole. Plant Physiol Biochem 30: 45-53
  • Briskin DP, S Basu, I Ho 1992. Studies on the reaction mechanism and transport function of P-type ATPases associated with the plant plasma membrane. In: DT Clarkson, DT Cooke, eds., Transport and Receptor Proteins of Plant Membranes, Plenum Publishing Co., New York, pp. 13-24
  • Lu Q, DP Briskin 1993. Modulation of the maize plasma membrane H+/NO3- symport carrier by NO3- as examined using isolated vesicles and 36ClO3- as a radiotracer analog for NO3-. Phytochemistry 33: 1-8
  • Schmidt AL, DP Briskin 1993. Energy transduction in tonoplast vesicles from red beet (Beta vulgaris L.) storage tissue. H+/substrate stoichiometries for the H+-ATPase and H+- PPase. Arch Biochem Biophys 301: 165-173
  • Schmidt AL, DP Briskin 1993. Reversal of the red beet tonoplast H+-ATPase by a pyrophosphate-generated proton electrochemical gradient. Arch Biochem Biophys 306: 407-414
  • Briskin DP 1994. Membranes and transport systems in plants: An overview. Weed Sci 42: 255-262
  • Briskin DP 1994. Solute transport across plant cell membranes: biochemical and biophysical aspects. In: M. Passarakli, ed., HANDBOOK OF PLANT AND CROP PHYSIOLOGY, Marcel-Decker, Press pp. 387-418
  • Basu S, DP Briskin 1995. Target molecular size suggesting a dimeric structure for the red beet plasma membrane Ca2+-ATPase. Phytochemistry 38: 15-17
  • Briskin DP, S Basu, SM Assmann 1995. Characterization of the red beet plasma membrane H+-ATPase reconstituted in a planar bilayer system. Plant Physiol 108: 393-398
  • Basu S, DP Briskin 1996. Chemical modification of essential arginine residues associated with the red beet (Beta vulgaris L.) plasma membrane Ca2+-ATPase. Phytochemistry 41: 685-689
  • Briskin DP, MC Gawienowski 1996. Role of the red beet plasma membrane H+-ATPase in K+ uptake. Plant Physiol 111: 1199-1207
  • Njoroge CK, EL Kerbel, DP Briskin 1998. Effect of calcium and calmodulin antagonists on ethylene biosynthesis in tomato fruits. J Sci Food Agric 76: 209-214
  • Njoroge CK, EL Kerbel, DP Briskin 1998. Effect of exogenous calmodulin and ATP on the activity of ethylene forming enzyme obtained from tomatoes and green pea pods. J Sci Food Agric 76: 215-220
  • Briskin DP, MC Gawienowski 1998. Evidence for voltage-sensitive reaction steps in the mechanism of the red beet plasma membrane H+-ATPase. Plant Physiol Biochem 36: 293-304
  • Bauerle C, C Magembe, DP Briskin 1998. Characterization of a red beet protein homologous to the essential Vma6p subunit of the yeast V-ATPase. Plant Physiol 117: 859-867
  • Gawienowski MC, SR Eckhoff, P Yang, PJ Rayapati, T Binder, DP Briskin 1999. Fate of maize DNA during steeping, wet-milling, and processing. Cereal Chem 76: 371-374
  • Satchivi N , EW Stoller, LM Wax, DP Briskin 2000. A non-linear dynamic simulation model for absorption and translocation of xenobiotics. I. Conceptual foundation and model development. Pesticide Biochem Physiol 68: 67-84
  • Satchivi N, EW Stoller, LM Wax, DP Briskin 2000. A non-linear dynamic simulation model for absorption and translocation of xenobiotics. II. Model Validation. Pesticide Biochem Physiol 68: 85-94
  • Briskin DP, A Leroy, MC Gawienowski 2000. Influence of nitrogen on the production of hypericins in the leaves of St. John's wort (Hypericum perforatum). Plant Physiol Biochem 38: 413-420
  • Briskin DP 2000. Medicinal plants and phytomedicines. Linking plant biochemistry and physiology to human health. Plant Physiol 124: 507-514
  • Satchivi N, LM Wax, EW Stoller, DP Briskin 2000. Absorption and translocation of glyphosate isopropylamine and trimethylsulfonium salts in Abutilon theophrasti and Setaria faberi. Weed Sci 48: 675-679
  • Briskin DP. 2001. Production of medicinal chemicals by plants. In: E Pessarakli, ed., HANDBOOK OF CROP AND PLANT PHYSIOLOGY, Marcel-Dekker, New York, pp. 485-500
  • Briskin DP, Gawienowski MC 2001. Differential Effects of Light and Nitrogen on Production of Hypericins and Leaf Glands in St. John's Wort (Hypericum perforatum L.) Plant Physiol Biochem 39: 1075-1081
  • Briskin DP, Kobayashi H, Mehta A, Gawienowski MC, Ainsworth L, Smith, MAL 2001 Production of Kavapyrones by Kava (Piper methysticum) Tissue cultures. Plant Cell Reports 20: 556-561
  • Satchivi NM, Stoller EW, Wax LM, Briskin DP 2001. A non-linear, dynamic simulation model for xenobiotic transport and whole plant allocation following foliar application. III. Influence of chemical properties, plant characteristics, and environmental parameters on xenobiotic absorption and translocation. Pesticide Biochem Physiol 71: 77-87
  • Smith, M.A.L., Kobayashi, H., Gawienowski, M. and Briskin, D.P. 2002. An in vitro approach to investigate medicinal chemical synthesis by three herbal plants. Plant Cell, Tissue and Organ Culture 70: 105-111
  • Rebeiz, C. A. Kolossov, V. L., Briskin, D., and Gawienowski, M. 2003. Chloroplast Biogenesis: Chlorophyll biosynthetic heterogeneity, multiple biosynthetic routes and biological spin-offs, Handbook of Photochemistry and Photobiology. (H. S. Nalwa ed.) Vol 4, pp. 183-268.
  • Briskin DP. 2004. Secondary metabolites as phytomedicines. ENCYCLOPEDIA OF PLANT AND CROP SCIENCES, Marcel-Dekker, New York, pp. 341-345
  • Briskin DP, Kobayashi H, Lila MA and MC Gawienowski. 2004. Kava (Piper methysticum): Growth in tissue culture and in vitro production of kavapyrones. In: L. Dyer, ed., PIPER. A MODEL GENUS FOR STUDIES OF CHEMISTRY, ECOLOGY AND EVOLUTION, Kluwer Academic/Plenum Publishing, New York, pp. 140-155
  • Satchivi NM, Stoller EW, Wax LM, Briskin DP 2006. A non-linear, dynamic simulation model for xenobiotic transport and whole plant allocation following foliar application. IV Structural requirements for optimum absorption and translocation. Pesticide Biochem Physiol 84: 83-97

Other Publications

  • Gawienowski, M.C., S.R. Eckhoff, P. Yang, P.J. Rayapati, T. Binder, and D.P. Briskin. (1999) Fate of maize DNA during steeping, wet-milling, and processing. Cereal Chem. 76:371-374.
  • Briskin, D.P., A. Leroy, and M.C. Gawienowski. (2000) Influence of nitrogen on the production of hypericins by St. John's wort. Plant Physiol. Biochem. 38:1-8.
  • Briskin, D.P. (2000) Medicinal chemicals and phytomedicines. Linking plant biochemistry and physiology to human health. Plant Physiol. 124:507-514.
  • Briskin, D.P. (2002) Production of phytomedicinal chemicals by plants. In: M. Pessarakli (ed.) "Handbook of Plant Physiology and Crop Physiology" (2nd ed.), Marcel-Decker Press, New York.